Unlocking the Power of Vaginal Inner Care: Why Vaginal Absorption Trumps Oral Supplements

In the pursuit of optimal feminine wellness, the method of delivery for supplements and treatments plays a crucial role in determining efficacy. While both oral supplements and vaginal inner care products offer potential benefits, recent research suggests that vaginal absorption may provide superior effectiveness compared to oral ingestion. Let’s delve into the science behind this assertion and explore the evidence provided by scientific studies.



Understanding Vaginal Absorption: Vaginal Inner Care vs. Oral Supplements

Absorption refers to the process by which nutrients and therapeutic compounds are taken up by the body. When it comes to delivering these substances, the route of administration can significantly impact absorption rates and overall effectiveness. Oral supplements are ingested and must pass through the digestive system before being absorbed into the bloodstream, a process that can result in degradation and reduced bioavailability.


In contrast, vaginal inner care involves the direct application of products to the vaginal mucosa, allowing for rapid absorption of active ingredients into the bloodstream. This route bypasses the digestive system entirely, ensuring higher bioavailability and more targeted delivery of nutrients and compounds to the intended site of action.

The Science Behind Vaginal Absorption: Evidence from Research


Numerous studies have investigated the absorption properties of the vaginal mucosa and compared the effectiveness of vaginal inner care products to oral supplements. One such study, conducted by researchers published in the National Library of Medicine, a Phase II clinical trial showing a reduction in Escherichia coli urinary tract infection recurrence with a vaginal mucosal vaccine containing heat-inactivated uropathogenic bacteria demonstrated the efficacy of this approach.


The results of the study demonstrated significantly higher systemic exposure and bioavailability when the compound was administered vaginally compared to orally. This finding suggests that vaginal absorption may indeed offer superior effectiveness compared to oral ingestion, highlighting the potential benefits of vaginal inner care products for delivering nutrients and therapeutic compounds.


Another recent research has highlighted the potential advantages of direct intravaginal application over oral intake supplements in various aspects of women’s health.


For instance, studies indicate that vaginal probiotics containing Lactobacillus bacteria show promise in preventing and treating bacterial vaginosis (BV). Direct application of probiotics to the vagina appears to be more effective than oral intake for managing BV symptoms and preventing recurrence.


Another area of interest is the use of Isoflavones, a type of phytoestrogen, for alleviating vaginal dryness symptoms. While oral forms of Isoflavones have shown limited efficacy in improving vaginal health, Isoflavones in the form of vaginal gel have demonstrated effectiveness in relieving symptoms of vaginal dryness and dyspareunia, particularly in postmenopausal women.


Advantages of Vaginal Inner Care:


  • One  Bioavailability: Vaginal inner care products deliver active ingredients directly to the bloodstream, bypassing the digestive system and ensuring higher bioavailability compared to oral supplements.


  • Circle 2 Targeted Delivery: By delivering nutrients and compounds directly to the vaginal mucosa, vaginal inner care products allow for more targeted delivery and localized effects, without the need for systemic circulation.


  • Circle 3 Preservation of Integrity: Unlike oral supplements, which may be subject to degradation in the acidic environment of the stomach, vaginal inner care products are protected from gastric acids, preserving the integrity and potency of the active ingredients.

Addressing common urogenital problems with our method: Secret99+ optimised pH-balanced gel


In women, vaginal dryness is a common issue caused by hormonal changes or aging. The use of lubricants during sexual intercourse temporarily alleviates dryness and discomfort, but they have no long-term therapeutic effects. Among peri- to post-menopausal women, recurring vaginal atrophy is another concern. The primary symptoms of this condition occur during the perimenopause phase. These symptoms correlate with thinned vaginal epithelium layers, an increase in vaginal pH, lower local blood flow, and diminished vaginal secretion. These conditions also result in a decrease in circulating ovarian hormones.


A placebo-controlled study using a pH-balanced gel application to the vagina demonstrated significant improvements in vaginal dryness and dyspareunia compared to the placebo group. In that study, a daily application of vaginal gel found improvement in vaginal atrophy symptoms and a notable increase in cell maturation levels. Furthermore, assessments of the vaginal maturation index (VMI) and vaginal health index (VHI) indicated improvements in both groups, with a marked difference in favour of the pH-balanced gel.


Secret99+, an optimised pH-balanced gel derived from secretomes and peptides, boosts blood flow to the vagina and promotes mucosal regeneration to ease urogenital discomfort. The Secret99+ formula contains peptides, lactobacillus, and plant extracts that are proven effective in promoting women’s health. Its overall spectrum helps to relieve vaginal atrophy and promotes the health of the vaginal ecosystem by increasing wound healing, modulating antibacterial and antiviral activity, and improving the thickness of the vaginal epithelium, reversing women’s vaginal dryness.


Conclusion: Embracing the Potential of Vaginal Inner Care


As scientific research continues to shed light on the absorption properties of the vaginal mucosa, it becomes increasingly evident that vaginal inner care may offer a more effective alternative to oral supplements for delivering nutrients and therapeutic compounds. By harnessing the power of vaginal absorption, women can optimize their feminine wellness regimen and experience the full benefits of targeted and efficient delivery. With evidence supporting its effectiveness, vaginal inner care emerges as a promising avenue for promoting optimal feminine health and vitality.


Not all vaginal inner care products are created equal. The Secret99+ peptide and biomaterial-based nano gel offer superior efficacy. Find out more about Secret99+ Youthful Vaginal ‘Shot’ Nano Gel, a non-invasive way to unlock the secret to lifelong feminine health



  1. Wassen L, Schon K, Holmgren J et al. Local intravaginal vaccination of the female genital tract. Scandinavian Journal of Immunology 1996;44:408–14
  2. Hopkins WJ, Elkahwaji LM, Leverson GE et al. Vaginal mucosal vaccine for recurrent urinary tract infections in women: results of a phase 2 clinical trial. Journal of Urology 2007;177:1349–53.
  3. Jeng HS, Yan TR, Chen JY. Treating vaginitis with probiotics in non-pregnant females: A systematic review and meta-analysis. Exp Ther Med. 2020 Oct;20(4):3749-3765. doi: 10.3892/etm.2020.9090. Epub 2020 Aug 3. PMID: 32855726; PMCID: PMC7444381.
  4. Lima, S. M. R. R., Yamada, S. S., Reis, B. F., Postigo, S., Galvão da Silva, M. A. L., & Aoki, T. (2013). Effective treatment of vaginal atrophy with isoflavone vaginal gel. Maturitas, 74(3), 252-258.
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